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Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.
Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.
Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia—a land of wooden slave quarters, faith healings, and voodoo—to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.
Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.
Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?
Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.
Amazon.com Review
Amazon Best Books of the Month, February 2010: From a single, abbreviated life grew a seemingly immortal line of cells that made some of the most crucial innovations in modern science possible. And from that same life, and those cells, Rebecca Skloot has fashioned in The Immortal Life of Henrietta Lacks a fascinating and moving story of medicine and family, of how life is sustained in laboratories and in memory. Henrietta Lacks was a mother of five in Baltimore, a poor African American migrant from the tobacco farms of Virginia, who died from a cruelly aggressive cancer at the age of 30 in 1951. A sample of her cancerous tissue, taken without her knowledge or consent, as was the custom then, turned out to provide one of the holy grails of mid-century biology: human cells that could survive--even thrive--in the lab. Known as HeLa cells, their stunning potency gave scientists a building block for countless breakthroughs, beginning with the cure for polio. Meanwhile, Henrietta's family continued to live in poverty and frequently poor health, and their discovery decades later of her unknowing contribution--and her cells' strange survival--left them full of pride, anger, and suspicion. For a decade, Skloot doggedly but compassionately gathered the threads of these stories, slowly gaining the trust of the family while helping them learn the truth about Henrietta, and with their aid she tells a rich and haunting story that asks the questions, Who owns our bodies? And who carries our memories? --Tom Nissley
Amazon Exclusive: Jad Abumrad Reviews The Immortal Life of Henrietta Lacks
Jad Abumrad is host and creator of the public radio hit Radiolab, now in its seventh season and reaching over a million people monthly. Radiolab combines cutting-edge production with a philosophical approach to big ideas in science and beyond, and an inventive method of storytelling. Abumrad has won numerous awards, including a National Headliner Award in Radio and an American Association for the Advancement of Science (AAAS) Science Journalism Award. Read his exclusive Amazon guest review of The Immortal Life of Henrietta Lacks:
Honestly, I can't imagine a better tale.
A detective story that's at once mythically large and painfully intimate.
Just the simple facts are hard to believe: that in 1951, a poor black woman named Henrietta Lacks dies of cervical cancer, but pieces of the tumor that killed her--taken without her knowledge or consent--live on, first in one lab, then in hundreds, then thousands, then in giant factories churning out polio vaccines, then aboard rocket ships launched into space. The cells from this one tumor would spawn a multi-billion dollar industry and become a foundation of modern science--leading to breakthroughs in gene mapping, cloning and fertility and helping to discover how viruses work and how cancer develops (among a million other things). All of which is to say: the science end of this story is enough to blow one's mind right out of one's face.
But what's truly remarkable about Rebecca Skloot's book is that we also get the rest of the story, the part that could have easily remained hidden had she not spent ten years unearthing it: Who was Henrietta Lacks? How did she live? How she did die? Did her family know that she'd become, in some sense, immortal, and how did that affect them? These are crucial questions, because science should never forget the people who gave it life. And so, what unfolds is not only a reporting tour de force but also a very entertaining account of Henrietta, her ancestors, her cells and the scientists who grew them.
The book ultimately channels its journey of discovery though Henrietta's youngest daughter, Deborah, who never knew her mother, and who dreamt of one day being a scientist.
As Deborah Lacks and Skloot search for answers, we're bounced effortlessly from the tiny tobacco-farming Virginia hamlet of Henrietta's childhood to modern-day Baltimore, where Henrietta's family remains. Along the way, a series of unforgettable juxtapositions: cell culturing bumps into faith healings, cutting edge medicine collides with the dark truth that Henrietta's family can't afford the health insurance to care for diseases their mother's cells have helped to cure.
Rebecca Skloot tells the story with great sensitivity, urgency and, in the end, damn fine writing. I highly recommend this book. --Jad Abumrad
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1,330 of 1,386 people found the following review helpful Thank you for this beautiful tribute to Henrietta Lacks, Amazon Verified Purchase This review is from: The Immortal Life of Henrietta Lacks (Hardcover) Wow. This book should be required reading for scientists and students of life. The true story of Henrietta Lacks and her family has finally been told, beautifully, in this book. The book encompasses science, ethics, and the story of a family who was terribly wronged in the pursuit of scientific research. I could gush about this book for pages but I'll try first to hit the main points of why this book is so remarkable in list form for the sake of brevity:1. The author clearly developed a strong relationship with the Lacks family, which was absolutely critical to ensuring the story was told accurately and with the respect to Henrietta Lacks that was so deeply deserved. 2. The storytelling is amazingly moving despite the need to convey a lot of scientific information. It reads like fiction. 3. Ms. Skloot's research into the science is impeccable. 4. The book is FAIR. It presents the unvarnished truth, obtained DIRECTLY from as many prinicpal... Read more 549 of 585 people found the following review helpful Captivating, engrossing, fascinating, heartbreaking, englightening...ALL in one stellar book!, This review is from: The Immortal Life of Henrietta Lacks (Hardcover) Customer review from the Amazon Vine™ Program (What's this?) This is hand's down one of the best books I've read in years and I wish I could give it more stars. It is going to be difficult to capture exactly what makes this book so outstanding and so captivating, but I'm going to give it my best shot.First of all I want to say I am STUNNED that this is the author's first book. She has poured ten years of her heart, soul, mind and her life in general in this book. What she has given birth to in that long period of labor is worthy of her sacrifice and honors Henrietta Lacks and her family. Other reviews have given the outline of this amazing story. What I want to stress is that Ms. Skloot has navigated the difficult terrain of respecting Mrs. Lacks and her family, while still telling their story in a very intimate, thorough, factual manner. What readers may not know is that the Lacks family isn't just a "subject" that the author researched. This is a real family with real heartaches and real challenges whose lives... Read more 372 of 405 people found the following review helpful 2010 Non-Fiction Award Winner?, This review is from: The Immortal Life of Henrietta Lacks (Hardcover) Customer review from the Amazon Vine™ Program (What's this?) As I recall this book was categorized as CANCER, I believe it might be more aptly described as science based non-fiction. In the last two decades I've seen occasional news items alluding to human cells taken from a black woman in the 1950's that have been replicated millions of times. The cells are referred to as HeLa and on the face of it I wouldn't have thought there was much of a story behind the extraction of these cells and their use by the biomed industry. However, this book dispells that rather naive assumption completely and puts a name and a face, a family, and a story behind the contents of many petri dishes and slides. THE IMMORTAL LIFE OF HENRIETTA LACKS explains how the cells were obtained, replicated, distributed, and used without informed consent of the owner and family by John Hopkins and how they benefitted mankind w/o compensation to the family. Author Skloot tells the story of a family victimized by socioeconomic conditions and racism that can't get fundamental... Read more |
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